치아우식증의 새로운 생체지표: nitric oxide와 glutathione
New biomarkers of dental caries: nitric oxide and glutathione
한동헌, 김민지, 전은주, 김진범,
소속 상세정보
한동헌 ( Han Dong-Hun ) - 서울대학교 치의학대학원 예방치학교실
김민지 ( Kim Min-Ji ) - 부산대학교 치의학전문대학원 예방치과학교실
전은주 ( Jun Eun-Joo ) - 부산대학교 치의학전문대학원 예방치과학교실
김진범 ( Kim Jin-Bom ) - 부산대학교 치의학전문대학원 예방치과학교실
KMID : 0362720120500090558
Abstract
Dental caries is multifactorial local disease which involves destruction of the hard tissues of the teeth by metabolities produces by microorganisms. Recently, there has been growing interest in the role of nitric oxide (NO) and glutathione (GSH) in caries incidence. The aim of the study was to survey the studies reported the association among salivary NO, GSH and dental careis. Three studies reported the association between NO and dental caries. However, the results were contradictory. Only one study showed negative association between GSH and dental caries. In Korea, NO showed negative association with Lactobacilli and GSH showed positive association with dental caries. These observations suggest the possibility that NO and GSH could be new biomarkers for dental caries. However, further study should be needed.
키워드
nitric oxide; glutathione; dental caries
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